The World Health Organization and Pan American Health Organization, Institut Pasteur and the networks of Fiocruz, CONSISE and ISARIC generated standardized clinical and epidemiological research protocols and questionnaires to address key public health questions. Specifically, data collected using the standardized protocols will be used to refine and update recommendations for prevention of Zika virus spread, surveillance and case definitions for microcephaly, to help understand the spread, severity, spectrum and impact on the community of ZIKV and to guide public health measures, particularly for pregnant women and couples planning a pregnancy.

Read the summary (pdf, 407kb)

These protocols have been designed to maximize the likelihood that data and biological samples are systematically collected and shared rapidly in a format that can be easily aggregated, tabulated and analyzed across many different settings globally. The protocols are listed below and can be adapted and used by research partners, Member States and the diverse institutions that comprise the global community. We encourage any and all study centres to contribute to these research efforts to better understand ZIKA.

The protocols above are still in a draft format and the information contained herein is subject to change.